Research Labs
A great deal of the most advanced instrumentation can be found in many of the individual laboratories carrying out research in chemical physics, nanoscale materials science, and biomolecular mass spectrometry, proteomics.
Among the state-of-the-art instruments are:
Bazemore-Walker Lab
Our newly renovated laboratory has a QSTAR Elite hybrid quadrupole time-of-flight mass spectrometer coupled to the Eksigent two-dimensional nano-LC via a nano-electrospray ionization source. MS/MS spectra are searched using ProteinPilot software, which combines the industry-standard Mascot (Matrix Science) search engine with the innovative Paragon search algorithm and the ProGroup software program (Applied Biosystems).
We also have the Agilent 1200 series binary HPLC system, Sutter Instruments P-2000 laser puller, and a Meiji stereo-microscope to support microcapillary column fabrication and testing. A newly built cell culture laboratory supports our bio-inspired research.
Diebold Lab
High power nanosecond and picosecond Nd:YAG lasers used in transient grating experiments, high resolution continuous dye and cw Ti:Sapphire lasers which are pumped with a diode pumped, continuous 532 nm laser.
Doll and Stratt Lab
The Rhode Island Network (RIN) for computational chemistry and physics has been the primary research instrument serving the shared scientific computing and visualization needs of a number of research groups at Brown. Established through multiple generations of joint National Science Foundation instrumentation grants, the RIN network is an integrated, high- performance Linux cluster. As currently configured, the RIN system consists of 53 nodes/106 processors. Individual processors in both systems are 1.67 GHz dual processor AMD Athlon units, each with 256 KB cache, and 1 GB memory per node. The nodes utilize 1 GB Ethernet connections. Disc storage is 80 GB for each compute node with a 1 TB RAID array for the system head node. In addition to individual desktop resources, RIN researchers have access to Brown's visualization center, including an immersive 4-wall cave graphics system.
Salomon Lab
Thermo-Finnigan LTQ-Fourier Transform Ion Cyclotron Resonance Mass Spectrometer plus extensive computational resources including 3 terrabyte, RAID-5 data server with automated tape backup, Sequest cluster, and custom-made relational database for the validation and visualization of large proteomic data sets
Seto Lab
96/384 well UV/fluorescence plate reader, isothermal titration microcalorimeter
Sun Lab
Bruker AXS D8- Advanced diffractometer with Cu Ka radiation (l = 1.5418 _) for structural studies of powders and thin films and a Lakeshore 7404 high sensitivity vibrating sample magnetometer (VSM) for magnetic studies.
Weber Lab
A regeneratively amplified, femtosecond pulsed laser systems, with 50 kHz repetition rate (80 fs pulses) and 5 kHz repetition rate (<50 fs pulses; energy of 0.5 mJ); molecular beam photoionization mass spectrometer and a photoelectron spectrometer.
Williard Lab
This X-Ray Crystallography facility utilizes a Bruker Smart Apex 3kW X-ray diffractometer.
The Departmental Research Support Staff also includes two Computer Support specialists who maintain the Department's extensive computing network of Linux, PC, and Mac-based workstations and computers, including web, file, and print servers, and an electronics technician. Purchasing, stockroom, grant management and secretarial personnel provide high level support to the Department's research and teaching activities.